A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they ...

A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they ...

How this approach differs from standard care Previous studies have shown that, for patients with four or fewer brain tumors, stereotactic radiation—which uses focused beams of high-dose radiation to ...

In patients with 5-20 brain metastases, stereotactic radiation improved symptoms and reduced interference with daily functioning compared to hippocampal-avoidance whole brain radiation. The weighted ...

In a Phase 3 randomized trial, Mass General Brigham researchers found that stereotactic radiation targeting individual tumors led to lower symptom burden, better cognitive outcomes, and better day to ...

Stereotactic radiation improved key quality-of-life outcomes among patients with multiple brain metastases compared with hippocampal-avoidance whole-brain radiation (HA-WBRT), a phase III randomized ...

Brain radiotherapy combined with ICIs improved overall survival and intracranial local control in SCLC patients with brain metastases. WBRT with simultaneous integrated boost (SIB) showed better ...

Radiation therapy targets lung cancer at all stages, damaging tumor cell DNA to inhibit growth and division. Palliative radiation focuses on symptom relief in polymetastatic disease, using shorter, ...

A phase 2 trial found that compared with whole brain radiation (WBRT), stereotactic radiation reduced neurologic deaths in patients with small cell lung cancer (SCLC) and 1-10 brain metastases. SCLC ...

How this approach differs from standard care Previous studies have shown that, for patients with four or fewer brain tumors, stereotactic radiation—which uses focused beams of high-dose radiation to ...