When rats and dogs were dosed with an active component, the client noticed their pharmacodynamics in vivo differed. The client wanted to understand the mechanism underlying these differences and ...

Have dreams of working in the medical or veterinary fields? UW’s human and animal physiology minor might be for you. This program equips students with the skills, education and experience needed to ...

A team developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip -- OPTECs-on-Chip -- that mimics in vivo renal physiology more closely than ever before. This model exhibits ...

The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a groundbreaking molecular mapping project that could reshape our understanding of renal health. Despite ...

In the lab, it’s easier to grow simple balls of cells than complex asymmetrical structures with two distinct ends—like the one million filtering units, or nephrons, that make up a human kidney. But ...

ENG: Confocal microscopy image of a kidney organoid on day 16 of differentiation. The cells have been labelled different colours using immunofluorescence to identify specific components: LTL (green: ...

An image of a mouse kidney glomerulus taken on a fluorescence microscope showing cell nuclei in blue, the PIEZO2 gene in magenta, and the renin gene in green. Each dot represents a single mRNA ...

Long-term lithium therapy remains the most effective maintenance treatment for bipolar disorder, yet it poses a significant risk of progressive renal impairment in a subset of patients. Early ...

Please provide your email address to receive an email when new articles are posted on . In a recent editorial, Beatrice Concepcion, MD, wrote despite some challenges, transplantation “remains the ...