In a paper published in the journal Neuron, researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic ...

Neuropathic pain is a devastating type of pain that significantly reduces the quality of life of affected people.

Neuropathic pain - abnormal hypersensitivity to stimuli - is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from ...

A team led by HHMI Hanna Gray Fellow Shan Meltzer has created a detailed, cell-by-cell map of the spinal cord that offers a new framework for understanding chronic pain and provides a powerful new ...

Pain is easy to understand until it isn't. A stubbed toe or sprained ankle hurts, but it makes sense because the cause is clear and the pain fades as you heal. Subscribe to our newsletter for the ...

How can patients and clinicians effectively manage diabetic neuropathic pain in 2024? At the French Diabetes Society congress, three experts provided a comprehensive overview of the treatment for ...

My back’s been bothering me, and everyone seems to have ideas what’s causing the pain. Can you help? ANSWER: Back pain is ...

Persistent neck pain accompanied by tingling in the fingers may signal cervical spine damage rather than simple fatigue. This expert-led piece explains key warning signs, risks like nerve compression ...

Sciatica pain can be prolonged by factors such as injury recurrence, underlying health conditions, and lifestyle choices that may hinder healing. Infections, spinal wear and tear, and in rare cases, ...

Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer ...