A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...
Scientists discover ALS protein that links DNA repair to cancer and dementia: Study ...
A protein, TDP43, previously linked to dementia and ALS, has been found to control DNA repair. Researchers say abnormal ...
Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...
Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy);(2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 ...
DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...